"T cell – centric view of ILC Differentiation"

James Di Santo

Innate Immunity Unit, Department of Immunology, Institut Pasteur, Paris, France

James Di Santo received a combined MD/PhD from Cornell Medical College and the Sloan Kette- ring Institute in NYC, pursued postdoctoral training with Pr Alain Fisher (Necker Hospital, Paris) and Pr Klaus Rajewsky (Institute for Genetics, Cologne) and has more than 30 years of experience in fundamental and translational immunology. The main interests of his laboratory at the Institut Pasteur (Paris) are in the areas of lymphocyte biology, cytokines, transcription factors and signaling pathways in the development and function of both adaptive (T and B cell) and innate lymphoid cells (ILC, NK cells) in mice and man. In parallel, over the last 20 years, his team has developed a series of humanized mouse models for the immune system that allows us to probe fundamental questions in human immunology especially in relation to infectious diseases. While largely fundamental in nature, his projects have a translational aim to impact in the clinics.