The 4th International Conference on Innate Lymphoid Cells (ILC4 2020), was originally scheduled to take place October 16-18, 2020 at the Palace Hotel in San Francisco, CA, USA. The unprecedented COVID-19 pandemic has precluded our ability to continue our science and to physically congregate safely at meetings to share our work.  As such, we have reluctantly cancelled the planned October International Innate Lymphocyte Conference in San Francisco (ILC4) and will plan to hold the meeting in the fall of 2021.  Dates, times and logistics will follow as we get a better handle on the status of the pandemic over the next months.  Please stay safe, continue great science, and we look forward to convening with all of you next year.

The theme of ILC4 is ILCs in tissue homeostasis and disease.

The aim of this international conference series is to provide an interactive platform for the exchange of new concepts, ideas and data between immunologists interested in ILCs and innate lymphocytes at large. ILCs are recently described tissue-resident cells increasingly implicated across a spectrum of diseases, including in humans. New methods, some rapidly evolving, have enabled a deeper look at the role of these cells in tissue health. Unappreciated plasticity, migration and functions are being uncovered every day, necessitating a timely update of standard methods, technologies and functional assays required for purification, imaging and analysis of ILCs with unprecedented detail, including single-cell sequencing and multi-parameter protein-based approaches. Attendees will learn the state-of-the-art current understanding of these fascinating cells from world experts in all facets of their biology.

Based on past biennial meetings (Paris, 2014; Berlin, 2016; Tokyo, 2018), we anticipate an attendance of 300- 350 participants for this three-day program. The primary objective of the program is to cover basic and translational aspects of innate lymphocyte biology in model mouse systems and in humans as well as their roles in tissue homeostasis, immune regulation and disease by combining talks by invited expert speakers and selected abstract submissions to be presented as oral or poster presentations.

There will be sessions dedicated to allergic, metabolic, neurologic, and other inflammatory diseases, as well as stem cells and cancer. The meeting will bridge the gap between the scientists performing basic research across the scope of these recently described cells and those working to harness this knowledge to develop strategies for interventions that restore tissue homeostasis.

The program will include invited expert speakers and selected abstract submissions to be presented as oral or poster presentations. Ample time will be reserved for networking, including a welcome reception, poster sessions and a Final Night Networking event at the award-winning Foreign Cinema restaurant in San Francisco.

Abstract submission will open on February 1st for poster presentations from which applicants will be selected by the Organizing Committee for oral presentations. We will also offer awards for poster presentations to encourage young and early-career researchers.

Abstract Submission Categories:

  • ILC Development and Trajectories
  • ILC Tissue Niches
  • ILC1s and NK cells
  • ILC2s
  • ILC3s
  • Central and Peripheral Nervous System and ILCs
  • ILCs and Metabolism
  • ILCs and Cancer
  • ILCs and Atopic Diseases
  • ILCs and Inflammatory Diseases
  • Human ILCs
  • Therapeutics

We look forward to receiving many applications from all over the world and to meeting you in San Francisco.


Richard Locksley, MD, Chair, University of California, Howard Hughes Medical Institute, San Francisco, USA

Erin Gordon, MD, University of California, San Francisco, USA

John Fahy, MD, MS, University of California, San Francisco, USA

Ari Molofsky, MD, PhD, University of California, San Francisco, USA